A Concurrent Review on Plant Derived Biopesticides and Synthetic Pesticides: Their Importance in Plant Protection and Impacts on Human Health

Authors

  • Abhiram Kumar Birla Institute of Technology and Sciences-Pilani, Hyderabad Campus, Hyderabad, Telangana 500078, India Author https://orcid.org/0000-0002-3422-2117
  • R. Venkat Ramchandar Birla Institute of Technology and Sciences Pilani Hyderabad Campus Author
  • Chhavi Dhiman Birla Institute of Technology and Sciences Pilani Hyderabad Campus Author
  • E. Priyanka Birla Institute of Technology and Sciences Pilani Hyderabad Campus Author
  • Dr. Madhu Rani Bharati Author
  • Dr. Laxmi Kant Bhardwaj Amity University, Noida, India-201303 Author
  • Dr. Piyush Khandeliaa Birla Institute of Technology and Sciences Pilani Hyderabad Campus Author
  • Dr. Kumar Pranav Narayan Pranav Birla Institute of Technology and Sciences Pilani Hyderabad Campus Author

DOI:

https://doi.org/10.46488/

Keywords:

Plant Protection, Synthetic pesticides, Biopesticides, Solanaceae family plants, Human health

Abstract

This review explores the impacts of synthetic pesticides and Biopesticides on human health, aiming to provide a comprehensive understanding of their benefits and risks. Currently, farmers are using synthetic pesticides to increase the yield of crop production, but they pose significant health risks, such as acute poisoning, cancer, endocrine disruption, anaphylactic shock and other severe health issues. On the other hand, Biopesticides, derived from natural organisms or plant-derived secondary metabolites, are considered safer alternatives, offering effective pest management with reduced risk to human health. This review draws attention to plant-derived material use in pest control management. Further, deciphering plant diseases with phytogenic bacteria and their control by organic bio-pesticide. Conclusively, this review suggests that future research should focus on integrated pest management approaches that combine the strengths of both synthetic and biopesticides applications while mitigating health risks. The findings underscore the imperative for ongoing evaluation of pesticide usage and provide a framework for informed decision-making regarding human exposure to these substances.

Author Biographies

  • Abhiram Kumar, Birla Institute of Technology and Sciences-Pilani, Hyderabad Campus, Hyderabad, Telangana 500078, India

    Mr. Kumar has completed his Bachelor of Pharmacy (B. Pharm) from Annamalai University, Tamilnadu, India, and a Master in Pharmaceutical Sciences from Uttarakhand Technical University, Dehradun. During his academic career, he gathered knowledge in Novel drug delivery and formulation development, optimization techniques, Quality by Design (QbD), and analytical method development. Abhiram has consistently demonstrated exceptional dedication, diligence, and expertise in their role as Onco nutrition product development, Animal cell culture, and analytical handling with HPLC, UPLC, and LCMS/MS. He possesses a deep understanding of their field, which is evident in their ability to tackle complex challenges with creativity and innovative solutions. Their keen analytical skills, combined with their strong communication abilities, make them an invaluable contributor to any collaborative project or team effort. He has worked in reputed multinational pharmaceutical companies M/S Ipca Laboratory Limited, M/S Alembic Pharmaceutical Limited, and research institute like CSIR-Central drug research Institute Lucknow, India. Currently, He is serving as R & D Head Incharge at M/S Esperer Onco Nutrition Pvt. Ltd. collaborating with Birla Institute of Technology and Sciences Pilani. In addition, He is pursuing a doctoral student from the Laboratory of Molecular Medicine, BITS-PILANI. He published research articles, review articles, and Book chapters in high-impact journals. Now, he is focused on developing a novel nano-immunomodulatory nutraceutical formulation for colon cancer theranostics.

  • R. Venkat Ramchandar, Birla Institute of Technology and Sciences Pilani Hyderabad Campus

    Assistant Professor at a Government Degree College in Telangana and about to submit a PhD thesis

  • E. Priyanka, Birla Institute of Technology and Sciences Pilani Hyderabad Campus

    PhD student 

  • Dr. Laxmi Kant Bhardwaj, Amity University, Noida, India-201303
    Dr. Laxmi Kant Bhardwaj -Amity University, Noida, India-201303. -Section Editor (Basic Sciences & Mathematics) for the Journal of Computers, Mechanical and Management, AAN Publishers, Malaysia.   -Editor-in-Chief for the Journal of Artificial Intelligence (SSRJAI), SSR Publisher.
  • Dr. Piyush Khandeliaa, Birla Institute of Technology and Sciences Pilani Hyderabad Campus

    Assistent professor at BITS-Pilani Hyderabad campus 

  • Dr. Kumar Pranav Narayan Pranav , Birla Institute of Technology and Sciences Pilani Hyderabad Campus

    Professor at BITS-Pilani Hyderabad Campus 

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September 2025 (Forthcoming Issue)

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Articles